alvaSketcher
alvaMolecule
alvaDesc
alvaModel
alvaRunner
alvaBuilder
Draw, Edit, and Prepare Your Chemical Structure
AlvaSketcher is a modern molecular editor for drawing, editing, and preparing 2D chemical structures. Designed for speed, precision, and ease of use, it provides an intuitive interface for creating molecules, making it the ideal companion for cheminformatics workflows.
Why Use alvaSketcher?
Fast and intuitive molecular editing: Create and modify chemical structures with responsive drawing tools, automatic bond and atom handling, and a workflow designed for both occasional users and expert chemists.
Comprehensive structure editing: Draw atoms, bonds, rings, chains, templates, reactions, and molecular annotations using an easy-to-use graphical interface.
Advanced selection and transformation tools: Select atoms or fragments and move, rotate, flip, copy, paste, or edit entire molecular substructures with just a few clicks.
Designed for interoperability: Import and export common chemical formats, making alvaSketcher an ideal companion for the Alvascience software suite and third-party cheminformatics tools.
Free for Academic and Non-Commercial Use: AlvaSketcher is freely available for academic research and non-commercial applications.
Modern Molecular Drawing
Creating chemical structures should be fast and natural.
AlvaSketcher provides an intuitive drawing environment where molecules can be created using atoms, bonds, rings, chains, and reusable templates. Automatic valence handling, atom typing, and geometry generation simplify the drawing process while allowing full manual control whenever needed.
Powerful Editing Tools
Editing existing molecules is just as important as creating them.
AlvaSketcher includes a comprehensive set of editing tools for modifying molecular structures:
- Move and edit atoms and bonds
- Rotate and flip selected fragments
- Copy and paste molecular substructures
- Delete or replace fragments
- Automatic coordinate cleanup
- Undo and redo support
These tools make structural modifications quick and efficient, even for complex molecules.
Video
A short video introduction:
Platforms
The software is 64bit and it’s available for Windows, Linux and macOS.
How To Cite
If you reference alvaSketcher in an academic paper or publication, you can find the correct citation for your version by selecting “About alvaSketcher” from its menu.
Additionally, please consider citing the following paper:
- Mauri, A., & Bertola, M. (2022). Alvascience: A New Software Suite for the QSAR Workflow Applied to the Blood–Brain Barrier Permeability. International Journal of Molecular Sciences, 23(21), 12882. https://doi.org/10.3390/ijms232112882